![]() The theory of helical diffraction was developed in parallel in the early 1950s by Cochran et al. ![]() ![]() The determination of the structures of the α-helix, the β-sheet, the triple helical structure of collagen and the double helix of DNA were all based on or confirmed by fibre diffraction analysis. The technique of fibre diffraction and the theory of helical diffraction were early developments in 20th century molecular structural studies and can be said to have formed a central part in the elucidation of the double-helical structure of DNA, which is probably the single greatest discovery in biology in recent times. ![]()
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